L'Isola di Esme is conveniently located in the popular Vatican area. Featuring a complete list of amenities, guests will find their stay at the property a comfortable one. Service-minded staff will welcome and guide you at the L'Isola di Esme. Each guestroom is elegantly furnished and equipped with handy amenities. The hotel offers various recreational opportunities. Discover all Rome has to offer by making L'Isola di Esme your base.